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In addition, Serine and arginine rich splicing factor 9 (SFRS9) can upregulate the expression of GPX4 by binding to GPX4 mRNA, which promote the growth of CRC, while SFRS9 knockdown significantly inhibited tumor growth in nude mice (Wang R

doi: 10.1016/j.jid.2020.05.103 90 NguyenMQTehJLFPurwinTJChervonevaIDaviesMANathansonKLet al

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A positive association between aconitase activity and GSH/GSSG was found in both cerebellum ( P =0.01) and BA22 ( P =0.03) in our combined case and control cohort (correlation coefficients=0.46 and 0.45, respectively)

There were no DILI fatalities (death or transplant) in the BLA group but 4 fatalities amongst 278 probable DILIs (1.4%) in the nBLA group